01 - Preheat oven to 400°F. Line a baking sheet with parchment paper.
02 - Toss butternut squash cubes, chopped onion, and garlic cloves with 1 tablespoon olive oil and a pinch of salt. Spread evenly on the prepared baking sheet and roast for 25 to 30 minutes until the squash is soft and starts to caramelize.
03 - Meanwhile, cook pasta according to package instructions. Drain and set aside.
04 - In a blender, combine roasted vegetables, soy or oat milk, nutritional yeast, lemon juice, Dijon mustard, turmeric, smoked paprika, ½ teaspoon salt, and black pepper. Blend until smooth and creamy. Adjust seasoning as needed.
05 - Heat 1 tablespoon olive oil in a large pot over medium heat. Pour in the blended sauce and cook for 2 to 3 minutes, stirring until heated through.
06 - Add cooked pasta to the sauce and stir to coat evenly.
07 - For a crunchy finish, preheat the broiler. Toss panko breadcrumbs with 1 tablespoon olive oil, sprinkle over the pasta mixture, and broil for 2 to 3 minutes until golden brown.
08 - Serve hot, optionally garnished with extra black pepper or fresh herbs.